Endoscopic Pituitary Surgery in Iran 2022

Endoscopic Pituitary Surgery in Iran

Endoscopic Pituitary Surgery in Iran

Pituitary adenoma is actually an abnormal growth of part of this pituitary gland and is inherently benign.
The pituitary gland is located in the middle line at the base of the skull and is responsible for controlling the most important glandular functions of the body.

Pituitary tumor

So, as mentioned, pituitary tumors arise from the abnormal growth of healthy pituitary cells and are considered benign brain tumors.

Symptoms of pituitary adenoma tumor

Thus, apart from the headache and loss of vision that commonly occurs due to the proximity of the pituitary gland to the optic nerves, the symptoms of patients with pituitary tumors depend on the type and location of the adenoma, such as:

Endoscopic Pituitary Surgery in Iran
Endoscopic Pituitary Surgery in Iran

Discharge of milk from the breast at a time other than breastfeeding and even in men,
Puberty disorders, diabetes mellitus and other heart problems,
Abnormal growth of limbs and face that occurs after puberty and causes the patient’s hands, feet and face to become large and rough.

Another symptom of pituitary tumors is “tasteless diabetes”; A type of overeating and urination that is caused by a decrease in hormonal secretion, whose job is to inhibit the excretion of water in the urine, and in its absence, a lot of water is excreted in the urine.

The reason why this symptom is called tasteless diabetes is that although the volume of urine in diabetic patients also increases, it is accompanied by the excretion of sugar, unlike these patients who only have more water excretion in their urine and less urinary sugar.

Is pituitary gland enlargement dangerous?

As mentioned, enlargement of the pituitary gland can cause a decrease in vision and loss of vision by creating a compressive effect on the optic nerve.

Treatment of pituitary adenoma

Treatment of a pituitary tumor (pituitary adenoma) depends entirely on the type of tumor; Medication, surgery, radiation therapy, and sometimes gamma rays are all used.
Drug therapy is used in 90% of cases of prolactin-secreting tumors, which will be mentioned below.

Endoscopic Pituitary Surgery in Iran

Pituitary tumor surgery is usually treated with an endoscope or microscope from inside the nose, and are the only rare cases that require cranial surgery, and are considered cranial base surgeries.
Although this surgery seems low risk and low complication, but it certainly has its risks and complications, but it is less dangerous than open skull surgery and requires special care and should be under the supervision of the best neurosurgeon in Iran and the best surgeon Pituitary to be performed in Iran.

Non-surgical treatment of pituitary adenoma

Radiation therapy and gamma rays are used for patients for whom surgery is either not possible, or has failed, or it is not possible to remove the entire tumor, or we have recurrent recurrences.

Prolactin

The most common type of pituitary adenoma is a prolactinoma, or tumor that secretes the hormone prolactin.
The secretion of this hormone naturally increases during breastfeeding and causes milk production, but if this tumor is present in the pituitary gland, milk will be produced and secreted in non-breastfeeding men as well.
The main treatment for this adenoma, unlike almost all other adenomas and brain tumors, is drug therapy.
 In many patients, even with very large masses, drug therapy responds well.
 Of course, there are cases in which this tumor also needs surgery, but these cases are very limited.
The most well-known drugs used for this tumor sometimes cause heart complications, which are not common, but the patient needs to be controlled in this regard.
Growth hormone-secreting adenoma causes the enlargement of almost all bone tissue and soft tissues in the body, which is called “acromegaly”; In this way, the patient’s arms and legs become larger and the patient’s ring and shoes become smaller;
The bones of the face become large and rough, and the person’s face changes, and even as the tongue enlarges, the patient’s speech changes.
In addition, bad breath, high blood pressure, high blood sugar and diabetes, heart failure and gastrointestinal tumors are some of the complications of this adenoma.

Symptoms of acromegaly

The main treatment for this tumor is surgery, and other treatments are used in certain conditions.
Immediately after successful surgery, the patient clearly feels light on the tongue and face, and if the disease is diagnosed in the early stages, some other symptoms will gradually go away, such as diabetes, high blood pressure, and heart failure, although they may remain to some degree. .

Symptoms of Cushing’s disease

Another type of these tumors increases the body’s secretion of corticosteroid hormones and is called “Cushing’s disease”.
 In this type, the patient experiences weight gain, thin skin, striae or broad lines of purple skin, roundness and redness of the face, high blood sugar, osteoporosis, and vulnerability to infections.
These tumors are also primarily treated with surgery, and if diagnosed and treated in time, irreversible complications such as osteoporosis can be prevented; However, the rate of response still depends on the progression of the disease.
There are rarer types of adenomas that secrete thyroid-stimulating hormone and sex hormones.
There is another form that does not secrete hormones.
In this type, there are no hormonal symptoms and these patients are usually examined and diagnosed with reduced vision.
In general, pituitary adenoma is a tumor different from other brain tumors; It has hormonal symptoms, is usually operated on through the nose, and although it is benign, it can recur and can cause serious complications in other parts of the body.

الدکتور مهدي زينلی الزادة – استاذ جراحة المخ و قاعدة الجمجمة

Endoscopic Pituitary Surgery in Iran

Dr. Mehdi Zeinalizadeh – professor in brain surgery and cranial base

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